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٠اÙبÙزÙÙ Menu Transferrin saturation is also called transferrin saturation index (TSI) or transferrin saturation percentage (TS %). In iron deficiency, the iron level is low but the TIBC is increased, thus transferrin saturation becomes very low. â eventberatung24 München â Agentur für Projektleitung und Beratung. It is the value of serum iron divided by the total iron-binding capacity of the available transferrin, the main protein that binds iron in the blood, this value tells a clinician how much serum iron is bound. A low percentage of transferrin saturation may be a sign of iron deficit in the body. This value is the ratio of serum iron and total iron binding capacity for human body.